Biosimilars – Forecast – Endocrinology

In 2021, sales of insulins at the ex-manufacturer price level exceeded $20 billion in the major pharmaceutical markets under study (United States, EU5, and Japan). Throughout our 2021-2031 forecast period, the originator insulins manufactured by Eli Lilly, Novo Nordisk, and Sanofi will face increasing competition from insulin biosimilars / follow-on insulins, eroding both patient share and drug prices. We present our forecasts for key reference brand insulins and their biosimilars / follow-on insulins by therapeutic area, molecule, and country / region.

Table of contents

  • Biosimilars - Forecast - Endocrinology
    • Market forecast in the major pharmaceutical markets
      • Major-market forecast: endocrinology biologics (insulin analogues)
      • Terminology
      • Overarching forecast assumptions
        • Overview of insulin brands in forecast
          • Overview of approved insulins
          • Biosimilar entry assumptions for approved insulins
        • Overview of insulin biosimilar assumptions
        • Drug-specific forecast assumptions
          • Lantus
            • Outlook for Lantus
            • First major-market biosimilar entrants
            • Order of entry in the United States
            • Order of entry in the EU5
            • Order of entry in Japan
            • Biosimilar uptake assumptions
            • Biosimilar and brand ex-manufacturing price assumptions
            • Lantus sales forecast in the United States: 2021-2031
            • Lantus sales forecast in the EU5: 2021-2031
            • Lantus sales forecast in Japan: 2021-2031
          • Toujeo
            • Outlook for Toujeo
            • First major-market biosimilar entrants
            • Order of entry in the United States
            • Order of entry in the EU5
            • Biosimilar uptake assumptions
            • Biosimilar and brand ex-manufacturing price assumptions
            • Toujeo sales forecast in the United States: 2021-2031
            • Toujeo sales forecast in the EU5: 2021-2031
          • Humalog / Humalog Mix
            • Outlook for Humalog / Humalog Mix
            • First major-market biosimilar entrants
            • Order of entry in the United States
            • Order of entry in the EU5
            • Order of entry in Japan
            • Biosimilar uptake assumptions
            • Biosimilar and brand ex-manufacturing price assumptions
            • Humalog / Humalog Mix sales forecast in the United States: 2021-2031
            • Humalog / Humalog Mix sales forecast in the EU5: 2021-2031
            • Humalog / Humalog Mix sales forecast in Japan: 2021-2031
          • NovoLog / NovoRapid and NovoMix
            • Outlook for NovoLog / NovoRapid and NovoMix
            • First major-market biosimilar entrants (NovoLog and NovoRapid)
            • First major-market biosimilar entrants (NovoMix)
            • Biosimilar uptake assumptions
            • Biosimilar and brand ex-manufacturing price assumptions
            • NovoLog / NovoRapid sales forecast in the United States: 2021-2031
            • NovoLog / NovoRapid sales forecast in the EU5: 2021-2031
            • NovoLog / NovoRapid sales forecast in Japan: 2021-2031
            • NovoMix sales forecast in the United States: 2021-2031
            • NovoMix sales forecast in the EU5: 2021-2031
            • NovoMix sales forecast in Japan: 2021-2031

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